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Transcriptome Profiling Associated with CARD11 Overexpression in Colorectal Cancer Implicates a Potential Role for Tumor Immune Microenvironment and Cancer Pathways Modulation via NF-κB

Case report: Tenosynovial giant cell tumor

The vast complexities of biology requireapproaches to build a complete picture, starting from single cells to tissuesand beyond. At 10x Genomics, we provide single-cell, spatial, and in situ innovationsthat fuel scientific discoveries and drive exponential progress. Unravel highlycomplex biological systems, while bringing into focus the details that mattermost.    Join this seminar organized by your…

Integration of Oncological Data into openEHR: A Path Towards Improved Cancer Care and Research

Molecular tumor board: molecularly adjusted therapy upon identification and functional validation of a novel ALK resistance mutation in a case of lung adenocarcinoma

Clonal evolution and blastic plasmacytoid dendritic cell neoplasm: malignancies of divergent hematopoietic lineages emerging from a common founding clone

Intravenous Ig Ameliorates Disease in a Murine Model of Anti–Laminin 332 Mucous Membrane Pemphigoid

Genome-wide DNA methylation-analysis of blastic plasmacytoid dendritic cell neoplasm identifies distinct molecular features

Epithelial and Mesenchymal-like Pancreatic Cancer Cells Exhibit Different Stem Cell Phenotypes Associated with Different Metastatic Propensities

Update: The molecular spectrum of virus-associated high-grade B-cell non-Hodgkin lymphomas

Diagnostic management of blastic plasmacytoid dendritic cell neoplasm (BPDCN) in close interaction with therapeutic considerations

The Molecular Tumor Board of the University Cancer Center Schleswig-Holstein has been certified as a center for personalized medicine by the DKG (Deutsche Krebsgesellschaft; German Cancer Society). Our cancer research unit provides bioinformatic services for the molecular tumor board since 2018. Further information: https://www.uksh.de/Das+UKSH/Presse/Presseinformationen/2024/Zentrum+f%C3%BCr+Personalisierte+Medizin+_+Onkologie+am+UKSH+zertifiziert-p-210243.html

We passed this years quality assessment for NGS sequencing. Since 2022 we participate in the external quality assessment programme for Next-Generation Sequencing by the BVDH (Berufsverband Deutscher Humangenetiker; association of german human genetics). Further information: https://bvdh-ringversuche.de/downloads/rvinfo/nextgenseq/2023/RV%20NGS%202023%20zusammenfassender%20Abschlussbericht_EN_65815cc73b6563_94970283.pdf

Extending cBioPortal for Therapy Recommendation Documentation in Molecular Tumor Boards: Development and Usability Study

Our CRC 1665 appplication „Determinants, meanings and implications of sex diversity in sociocultural, medical and biological landscapes“ is funded. We are involved in two work packages using our spatial transcriptomics expertise and in data management.  https://www.uni-luebeck.de/aktuelles/nachricht/artikel/neuer-sonderforschungsbereich-fuer-die-erforschung-der-vielfalt-des-biologischen-geschlechts.html

Receptor repertoires of murine follicular T helper cells reveal a high clonal overlap in separate lymph nodes in autoimmunity

PD-L1 Dependent Immunogenic Landscape in Hot Lung Adenocarcinomas Identified by Transcriptome Analysis

Genomic insights into the pathogenesis of Epstein-Barr virus-associated diffuse large B-cell lymphoma by whole-genome and targeted amplicon sequencing

Effect of Differences in the Microbiome of Cyp17a1-Deficient Mice on Atherosclerotic Background