Welcome to website of the Group for Medical Systems Biology

The Medical Systems Biology group focuses on the computational investigation and integration of multi-omics data in explorative, preventative, and therapeutic contexts.

About us
We deploy concepts from non-linear dynamics and complex systems to develop mathematical models that unravel the self-organizing principles behind the interactions with biological entities.
Team

The complementary experience and research emphases of our team allow integrating all scales of resolution from genetic code to phenotypic expression.

Meet The Team

News and publications

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Nov02

New scientific article on Cancers

Prognostic Value of Regnase-1 in High-Grade Soft Tissue Sarcoma: Favourable in UPS, Yet Inverted in Adjuvantly Irradiated Patients
Nov02

New scientific article/abstract on European Heart Journal

Beyond typical lipid suspects-identification of sphingolipid metabolism as a pharmacotherapeutic target in calcific aortic valve disease
Oct20

Congratulations to Byambadolgor Munkhbaatar

Congratulations on earning your master’s degree Byambadolgor Munkhbaatar! We’re so incredibly happy for you and proud of all your hard work and achievements. Now that
Sep25

New scientific Paper on Movement Disorders

Transcriptome-Based Identification of ZZEF1 and ENTPD5 as Candidate Genes for Dystonia
Sep18

New scientific article on Cell Death & Disease

Westernized diet related arachidonic acid metabolism expands DNA error-prone growth factor-dependent colonic quiescent stem cells in adolescent mice

Service & Research Units

In the medical context, we work in cooperation with clinical facilities and research groups in the exploration of disease etiology, identification of pathways , and the development of treatment options in personalized medicine.

Bioinformatics Service Unit

We can advise on project planning to clarify at an early stage whether specific scientific questions can be answered within your experimental planning to avoid future complications.

Single Cell Genomics Research Group

New sequencing technologies have revolutionized genome research over the last decade.

Cancer Research Unit

What are the molecular drivers in tumor progression? How can current methods of molecular medicine, sequencing, and machine learning in the clinical diagnostics and routine be transferred?

Projects

A particular focus is put on the field of cancer research which culminated in the design of computational diagnostics pipelines for the Molecular Tumor Board at the UKSH Lübeck, which is an interface between clinical treatment and cutting-edge scientific insights by applying state-of-the-art sequencing and analysis approaches to the most challenging cases.

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Career

Join the Medical Systems Biology group

The group for Medical Systems Biology focuses on the development and verification of mathematical models for cellular behavior and cell communication from an initial stimulus to the final phenotype.

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