Welcome to website of the Group for Medical Systems Biology

The Medical Systems Biology group focuses on the computational investigation and integration of multi-omics data in explorative, preventative, and therapeutic contexts.

About us
We deploy concepts from non-linear dynamics and complex systems to develop mathematical models that unravel the self-organizing principles behind the interactions with biological entities.
Team

The complementary experience and research emphases of our team allow integrating all scales of resolution from genetic code to phenotypic expression.

Meet The Team

News and publications

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Feb13

New publication on ACS Pharmacology & Translational Science

Target Class Repurposing Across Membrane Transporter Families Provides Privileged Ligands to Address Specific and Undruggable Pharmacological Targets
Feb13

New publication on Annals of Clinical and Translational Neurology

Complementarity of Long-Reads and Optical Mapping in Parkinson’s Disease for Structural Variants
Feb13

New publication on Allergy, European Journal of Allergy and Clinical Immunology

Immune Training of the Interleukin 6 Gene in Airway Epithelial Cells is Central to Asthma Exacerbations
Nov25

New publication in post-COVID syndromes posted on Nature Communications

scRNA-seq reveals persistent aberrant differentiation of nasal epithelium driven by TNFα and TGFβ in post-COVID syndrome
Nov20

This is us

We just took a new group photo of all of us.

Service & Research Units

In the medical context, we work in cooperation with clinical facilities and research groups in the exploration of disease etiology, identification of pathways , and the development of treatment options in personalized medicine.

Bioinformatics Service Unit

We can advise on project planning to clarify at an early stage whether specific scientific questions can be answered within your experimental planning to avoid future complications.

Single Cell Genomics Research Group

New sequencing technologies have revolutionized genome research over the last decade.

Cancer Research Unit

What are the molecular drivers in tumor progression? How can current methods of molecular medicine, sequencing, and machine learning in the clinical diagnostics and routine be transferred?

Projects

A particular focus is put on the field of cancer research which culminated in the design of computational diagnostics pipelines for the Molecular Tumor Board at the UKSH Lübeck, which is an interface between clinical treatment and cutting-edge scientific insights by applying state-of-the-art sequencing and analysis approaches to the most challenging cases.

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Career

Join the Medical Systems Biology group

The group for Medical Systems Biology focuses on the development and verification of mathematical models for cellular behavior and cell communication from an initial stimulus to the final phenotype.

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