About us
We deploy concepts from non-linear dynamics and complex systems to develop mathematical models that unravel the self-organizing principles behind the interactions with biological entities.

The complementary experience and research emphases of our team allow integrating all scales of resolution from genetic code to phenotypic expression.


A particular focus is put on the field of cancer research which culminated in the design of computational diagnostics pipelines for the Molecular Tumor Board at the UKSH Lübeck, which is an interface between clinical treatment and cutting-edge scientific insights by applying state-of-the-art sequencing and analysis approaches to the most challenging cases.

News and publications

New publication in Leukemia

Genome-wide DNA methylation-analysis of blastic plasmacytoid dendritic cell neoplasm identifies distinct molecular features

New publication in Cancers

Epithelial and Mesenchymal-like Pancreatic Cancer Cells Exhibit Different Stem Cell Phenotypes Associated with Different Metastatic Propensities

New publication in Blood Reviews

Update: The molecular spectrum of virus-associated high-grade B-cell non-Hodgkin lymphomas

New publication in Annals of Hematology

Diagnostic management of blastic plasmacytoid dendritic cell neoplasm (BPDCN) in close interaction with therapeutic considerations

Certification as Center for Personalized Medicine – Oncology

The Molecular Tumor Board of the University Cancer Center Schleswig-Holstein has been certified as a center for personalized medicine by the DKG (Deutsche Krebsgesellschaft; German


Join the Medical Systems Biology group

The group for Medical Systems Biology focuses on the development and verification of mathematical models for cellular behavior and cell communication from an initial stimulus to the final phenotype.